THIS IS WHO WE ARETHESE ARE OUR BLENREP STORIES

Learn about real patient experiences with BLENREP

For adults with relapsed/refractory multiple myeloma who have received at least 4 prior therapies.

Everyone’s experience with relapsed/refractory multiple myeloma (RRMM) is unique, but there can be a lot to learn from other people’s stories. Select a patient ambassador photo for more information.

Individual results may vary.

Headshot of Kathy from Patient Stories

Kathy

- 59 years old

- Wife, mother, and substitute teacher

- More than 9 previous regimens for RRMM

 

Headshot of Cynthia from Patient Stories

Cynthia

- 65 years old

- Commercial photographer

- More than 4 previous regimens for RRMM

 

This is who I am.

Kathy

View Transcript

VO AND SUPER:

BLENREP

belantamab

mafodotin-blmf

for injection 100 mg

 

WHAT IS BLENREP?

BLENREP is a prescription medicine used to treat adults with multiple myeloma who have received at least 4 prior medicines to treat multiple myeloma, and their cancer has come back or did not respond to prior treatment. It is not known if BLENREP is safe and effective in children.

BLENREP is approved based on patient response rate. Studies are ongoing to confirm the clinical benefit of BLENREP for this use.

 

IMPORTANT SAFETY INFORMATION

 

What is the most important information I should know about BLENREP?

Before you receive BLENREP, you must read and agree to all of the instructions in the BLENREP Risk Evaluation and Mitigation Strategy, or REMS. Before prescribing BLENREP, your healthcare provider will explain the BLENREP REMS to you and have you sign the Patient Enrollment Form.

 

BLENREP can cause serious side effects, including:

Eye problems. Eye problems are common with BLENREP. BLENREP can cause changes to the surface of your eye that can lead to dry eyes, blurred vision, worsening vision, severe vision loss, and corneal ulcer. Tell your healthcare provider if you have any vision changes or eye problems during treatment with BLENREP.

 

SUPER: Please see IMPORTANT SAFETY INFORMATION continued at the end of this video and full Prescribing Information, including BOXED WARNING and Medication Guide.

 

VO: My name is Kathy. I’m a wife, mother, world traveler, and I’ve lived with multiple myeloma for the last 20 years.

 

SUPER: Kathy

 

VO: I didn’t stand idly by, doing nothing. I chose to be a pioneer in my journey with this disease and find a path forward.

 

SUPER: Be a pioneer in this disease… find a path forward

 

VO: I’ve been on more than 9 treatment regimens for multiple myeloma since I was diagnosed.

 

SUPER: Struggling with multiple relapses

 

VO: Each worked for a time, but in early 2020, my cancer stopped responding to the treatment.

 

VO: As I was getting weaker, my myeloma was getting stronger.

 

VO: In fact, I needed my husband to carry me up and down my 3-story townhouse.

 

VO: My husband and I did what we always did and started searching to find other options—

 

VO: researching multiple myeloma-based professional sites—

 

SUPER: Searching for options that provide hope

 

VO: patient advocacy groups, pharma company sites, social media, and even chat rooms.

 

VO: This led us to finding BLENREP, a potentially promising agent, so we went straight to my hematologist with our discovery.

 

SUPER: Finding BLENREP

 

VO: We brought it to their attention that a BCMA-inhibitor targeting drug… I had not tried.

 

SUPER: BCMA=B-cell maturation antigen.

 

VO: Time was of the essence, so I immediately asked about BLENREP. It’s important to be an advocate for your health and be proactive.

 

VO: My care team didn’t have experience with it, but after evaluating and discussing it with my doctor, and working out logistics, I was well on my way to getting it.

 

VO: My care team worked hard for me. My hematologist, nurse, and eye doctor are all under the same system, so my nurse was able to coordinate all my appointments.

 

VO: We talked about it in October, I got enrolled in BLENREP REMS, and got my first treatment in early November.

 

VO: Don’t give up, get that second opinion, be proactive in your care and—

 

VO: knowledge… you need to find out what kind of myeloma you have, and what kind of treatment options are available.

 

VO: You have to think of the long game with multiple myeloma.

 

VO: The disease is different for each person and each person responds differently, but you must be proactive.

 

VO: Just to keep fighting, and not to give up.

 

VO: I found out I might have vision problems with treatment through my own research—

 

VO: my hematologist gave me more detailed information and told me I’d need an eye exam prior to each infusion.

 

VO: Since starting treatment, I have been using eye drops multiple times a day as my eye doctor instructed me to do.

 

SUPER: Managing ocular side effects

 

VO: I have experienced dry eyes and some blurry vision, and my doctor has adjusted my treatment dose to manage the side effects.

 

VO: My treatment was a 30-minute infusion, every 3 weeks. And after 2 doses of BLENREP, I saw a response. I felt my body was in a better place.

 

SUPER: Responding to BLENREP

 

SUPER: Treatment results may vary.

 

VO: After two treatments of BLENREP, when I had the PET scan done, I was called pretty much immediately when the results were in by my doctor.

 

VO: I still wanted to have that report in my hands, and my husband finally showed up in our portal at like 4 in the morning.

 

VO: And so, he printed it and surprised me with it under our Christmas tree.

 

VO: And it was the best gift.

 

VO: I would tell other people in similar situations to stay strong and not give up.

 

VO: I feel blessed to have gotten BLENREP—it’s working for me and helping me stay focused on the positive.

 

SUPER: Staying positive during treatment

 

SUPER: Treatment results may vary.

 

VO: Never give up, because BLENREP could make a difference.

 

SUPER: Ask your healthcare provider if BLENREP is an appropriate option for you.

 

VO AND SUPER:

 

IMPORTANT SAFETY INFORMATION

  • Your healthcare provider will send you to an eye specialist to check your eyes before you start treatment with BLENREP, prior to each dose of BLENREP, and for worsening symptoms of eye problems.
  • Even if your vision seems fine, it is important that you get your eyes checked during treatment with BLENREP because some changes can happen without symptoms and may only be seen on an eye exam.
  • You should use preservative-free lubricant eye drops at least 4 times per day during treatment with BLENREP as instructed by your healthcare provider.
  • You should use caution when driving or operating machinery as BLENREP may affect your vision.
  • Avoid wearing contact lenses during treatment with BLENREP unless directed by your eye specialist.

 

Decrease in platelets (thrombocytopenia) is common with BLENREP, and can also be serious. Platelets are a type of blood cell that help your blood to clot. Your healthcare provider will check your blood cell counts before you start treatment with BLENREP and during treatment. Tell your healthcare provider if you have bleeding or bruising during treatment with BLENREP.

 

Infusion reactions are common with BLENREP, and can also be serious. Tell your healthcare provider or nurse right away if you get any of the following signs or symptoms of an infusion reaction while receiving BLENREP:

  • chills or shaking
  • redness of your face (flushing)
  • itching or rash
  • shortness of breath, cough, or wheezing
  • swelling of your lips, tongue, throat, or face
  • dizziness
  • feel like passing out
  • tiredness
  • fever
  • feel like your heart is racing (palpitations)

 

The most common side effects of BLENREP include vision or eye changes such as findings on eye exam (keratopathy), decreased vision or blurred vision, nausea, low blood cell counts, fever, infusion-related reactions, tiredness, and changes in kidney or liver function blood tests.

 

Before receiving BLENREP, tell your healthcare provider about all of your medical conditions, including if you:

  • have a history of vision or eye problems.
  • have bleeding problems or a history of bleeding problems.
  • are pregnant or plan to become pregnant. BLENREP can harm your unborn baby. Females who are able to become pregnant: Your healthcare provider may do a pregnancy test before you start treatment with BLENREP. You should use effective birth control during treatment with BLENREP and for 4 months after the last dose. Talk to your healthcare provider about birth control methods you can use during this time. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with BLENREP. Males with female partners who are able to become pregnant should use effective birth control during treatment with BLENREP and for 6 months after the last dose.
  • are breastfeeding or plan to breastfeed. It is not known if BLENREP passes into your breast milk. Do not breastfeed during treatment with BLENREP and for 3 months after the last dose.
  • BLENREP may affect fertility in males and females. Talk to your healthcare provider if this is a concern for you.

 

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

These are not all the possible side effects of BLENREP.

 

Please see Prescribing Information, including BOXED WARNING and Medication Guide.

 

VO AND SUPER: Ask your healthcare provider if BLENREP is an appropriate option for you.

 

SUPER: Trademarks are owned by or licensed to the GSK group of companies.

 

©2021 GSK or licensor.
BLMVID210018 November 2021
Produced in USA.

BLENREP has worked for me. It is helping me stay positive and stay ahead of this disease.

Who am I?

  • A wife, mother, and substitute teacher
  • 59 years old, diagnosed with multiple myeloma in 2001
  • More than 9 previous treatment regimens for multiple myeloma

What is my experience with BLENREP?

  • Began treatment in 2020 and had a response
  • Have experienced some side effects, including dry eye and blurred vision. Dry eye is managed with preservative-free lubricant eye drops during the day
  • Feel supported by a team of healthcare providers, including a nurse practitioner, eye care professional, and oncologist

Everyone’s disease is different and everyone responds differently. I try to be as proactive as I can, and BLENREP is part of that.

This is who I am.

Cynthia

View Transcript

VO AND SUPER:

BLENREP
belantamab
mafodotin-blmf
for injection 100 mg

 

WHAT IS BLENREP?
BLENREP is a prescription medicine used to treat adults with multiple myeloma who have received at least 4 prior medicines to treat multiple myeloma, and their cancer has come back or did not respond to prior treatment. It is not known if BLENREP is safe and effective in children.

 

BLENREP is approved based on patient response rate. Studies are ongoing to confirm the clinical benefit of BLENREP for this use.

 

IMPORTANT SAFETY INFORMATION

 

What is the most important information I should know about BLENREP?
Before you receive BLENREP, you must read and agree to all of the instructions in the BLENREP Risk Evaluation and Mitigation Strategy, or REMS. Before prescribing BLENREP, your healthcare provider will explain the BLENREP REMS to you and have you sign the Patient Enrollment Form.

 

BLENREP can cause serious side effects, including:

Eye problems. Eye problems are common with BLENREP. BLENREP can cause changes to the surface of your eye that can lead to dry eyes, blurred vision, worsening vision, severe vision loss, and corneal ulcer. Tell your healthcare provider if you have any vision changes or eye problems during treatment with BLENREP.

 

SUPER: Please see IMPORTANT SAFETY INFORMATION continued at the end of this video and full Prescribing Information, including BOXED WARNING and Medication Guide.

 

VO: Hello, I’m Cynthia. I’m a wife, a proud mother to 7 children, a grandmother to 6 beautiful grandchildren, and an avid photographer.

 

SUPER: CYNTHIA

 

VO: I’ve been through a lot with multiple myeloma, but I’m a tough cookie. I try to live each day of my life to the fullest.

 

SUPER: Cynthia is a real patient taking BLENREP. [GSK paid her for her time and expenses for sharing her unique experience.] Individual results may vary.

 

SUPER: TRY TO LIVE EACH DAY TO THE FULLEST

 

VO: Over the last 6 years I’ve had more than 4 relapses, and been on nearly every treatment imaginable.

 

SUPER: ON NEARLY EVERY TREATMENT IMAGINABLE

 

VO: Throughout my disease my doctors had me on combination regimens with an immunomodulatory agent, and then another with a proteasome inhibitor. When that failed, I was on another combination with an anti-CD38 monoclonal antibody.

 

VO: I’d respond to a treatment for a while, but then that would eventually stop, and I’d have to move on to another one. Last year, relapse hit me particularly hard. I’d wake up not knowing what was going to happen. I didn’t know if I would get sick, feel dizzy, or have enough energy to get up the stairs.

 

VO: Both my doctor and my nurse were eagerly waiting for a treatment to get approved called BLENREP.

 

VO: They told me it attacked the myeloma cells in a very different way than previous therapies I had tried. Patients in the trial responded, and there was a chance that I could respond, too.

 

VO: When BLENREP got approved, all I could do was cry. I felt very hopeful.

 

SUPER: FEELING HOPEFUL WITH BLENREP

 

VO: My nurse told me I would have to see an eye doctor to get an eye exam before every dose of BLENREP, and I was also enrolled in the BLENREP REMS. All of this was worth the effort to finally get treatment.

 

VO: BLENREP did come with some potential vision issues I was worried about because I’m a photographer, and I need my eyes.

 

VO: Some days, things look very blurry, and it feels like there’s sandpaper in my eyes, but other days, it’s not so bad.

 

SUPER: Individual results may vary.

 

VO: As part of the treatment, I've been using lubricant eye drops every 4 hours, as my nurse instructed me to do. I see a local ophthalmologist who calls my nurse directly after every eye exam to share the results, so my doctor can determine the course of my treatment.

 

SUPER: MANAGING OCULAR SIDE EFFECTS

 

VO: After my doctor determines I can get treatment, my nurse schedules my appointments for the 30-minute BLENREP infusion. I had to go through some initial dose adjustments, including dose holds, when I started BLENREP, due to the vision issues. But after finding the right one, in time, I started to respond to treatment.

 

SUPER: RESPONDING TO BLENREP

 

SUPER: Treatment results may vary.

 

VO: I’m enjoying my kids and grandkids, and tell others with this disease to try to live life to the fullest and stay positive as much as you can.

 

SUPER: STAYING POSITIVE IN MY JOURNEY

 

SUPER: Treatment results may vary.

 

SUPER: Ask your healthcare provider if BLENREP is an appropriate option for you.

 

VO AND SUPER:

 

IMPORTANT SAFETY INFORMATION

  • Your healthcare provider will send you to an eye specialist to check your eyes before you start treatment with BLENREP, prior to each dose of BLENREP, and for worsening symptoms of eye problems.
  • Even if your vision seems fine, it is important that you get your eyes checked during treatment with BLENREP because some changes can happen without symptoms and may only be seen on an eye exam.
  • You should use preservative-free lubricant eye drops at least 4 times per day during treatment with BLENREP as instructed by your healthcare provider.
  • You should use caution when driving or operating machinery as BLENREP may affect your vision.
  • Avoid wearing contact lenses during treatment with BLENREP unless directed by your eye specialist.

Decrease in platelets (thrombocytopenia) is common with BLENREP, and can also be serious. Platelets are a type of blood cell that help your blood to clot. Your healthcare provider will check your blood cell counts before you start treatment with BLENREP and during treatment. Tell your healthcare provider if you have bleeding or bruising during treatment with BLENREP.

 

Infusion reactions are common with BLENREP, and can also be serious. Tell your healthcare provider or nurse right away if you get any of the following signs or symptoms of an infusion reaction while receiving BLENREP:

  • chills or shaking
  • redness of your face (flushing)
  • itching or rash
  • shortness of breath, cough, or wheezing
  • swelling of your lips, tongue, throat, or face
  • dizziness
  • feel like passing out
  • tiredness
  • fever
  • feel like your heart is racing (palpitations)

VO:

 

The most common side effects of BLENREP include vision or eye changes such as findings on eye exam (keratopathy), decreased vision or blurred vision, nausea, low blood cell counts, fever, infusion-related reactions, tiredness, and changes in kidney or liver function blood tests.

 

Before receiving BLENREP, tell your healthcare provider about all of your medical conditions, including if you:

  • have a history of vision or eye problems.
  • have bleeding problems or a history of bleeding problems.
  • are pregnant or plan to become pregnant. BLENREP can harm your unborn baby. Females who are able to become pregnant: Your healthcare provider may do a pregnancy test before you start treatment with BLENREP. You should use effective birth control during treatment with BLENREP and for 4 months after the last dose. Talk to your healthcare provider about birth control methods you can use during this time. Tell your healthcare provider if you become pregnant or think you may be pregnant during treatment with BLENREP. Males with female partners who are able to become pregnant should use effective birth control during treatment with BLENREP and for 6 months after the last dose.
  • are breastfeeding or plan to breastfeed. It is not known if BLENREP passes into your breast milk. Do not breastfeed during treatment with BLENREP and for 3 months after the last dose.
  • BLENREP may affect fertility in males and females. Talk to your healthcare provider if this is a concern for you.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

 

These are not all the possible side effects of BLENREP.

 

Please see Prescribing Information, including BOXED WARNING and Medication Guide.

 

VO AND SUPER:

 

Ask your healthcare provider if BLENREP is an appropriate option for you.

 

SUPER: Trademarks are owned by or licensed to the GSK group of companies.

 

©2021 GSK or licensor.
BLMVID210029 November 2021
Produced in USA.

BLENREP works in different ways and this gave me hope.

Who am I?

  • A commercial photographer specializing in newborn photography: a “baby whisperer”
  • 65 years old, diagnosed with multiple myeloma in 2015
  • More than 4 previous treatment regimens for multiple myeloma
  • Married to my high school sweetheart for 47 years
  • 7 children, 5 of whom are adopted; 6 grandchildren
  • As a foster parent to medically fragile newborns, took care of about 60 children over the course of 25 years

What is my experience with BLENREP?

  • Managing the disease with support from family and friends for the past 6 years 
  • Have experienced fatigue, blurred vision, and eye discomfort, but have coped with these side effects and respond to BLENREP treatment*
  • A nurse practitioner has been an important member of the support team, providing encouragement and attentive care

*Treatment results may vary.

When BLENREP got approved, all I could do was cry. I felt very hopeful.

Have you thought about telling your BLENREP story?

Call 1-877-268-0443 to learn more about the BLENREP patient ambassador program.

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Image: Woman on Tablet
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Speak to a doctor about whether BLENREP may be appropriate for you or a loved one with relapsed/refractory multiple myeloma.